There are a few reasons why you might be unable to renew a title:
Someone else has the book on hold. In this case, you'll see a Place Hold button (instead of Renew), which means you need to wait to borrow the book again.
It's too early to renew the book. You'll be able to renew a book a few days before it's due. If it's too early, Libby will tell you how much longer you need to wait before you can renew it.
This book is no longer in your library's catalog. This may happen because the book has expired or has been manually removed.